Prof Andrew Spillane MD FRACS

Surgical Oncology

Prof Andrew Spillane

Prof Andrew Spillane

Clinical practice:

Surgical management of breast cancer, melanoma and soft tissue tumours such as sarcoma. Includes sentinel lymph node biopsy, regional lymph node dissection, breast reconstruction and oncoplastic breast surgery techniques. Consults at North Sydney.

Hospital appointments (regular operating lists):

The Mater and Royal North Shore Hospitals.

Andrew Spillane is Professor of Surgical Oncology at The University of Sydney, Northern Clinical School. He specialises in the surgical management of breast cancer and melanoma. Andrew is a senior VMO surgeon at the Mater North Sydney, Royal North Shore Hospital and North Shore Private Hospitals.

Andrew is a member of the founding council and past President of Breast Surgeons of Australia and New Zealand Inc. (BreastSurgANZ) and still actively engages in the Post-fellowship Training Committee and BreastSurgANZ Quality Audit Committee. He is a board member, member of the scientific advisory committee and member of the finance and risk committee of the Breast Cancer Trials (formerly ANZBCTG) and BCT breast surgery Craft Group Lead. He is also a board member and Deputy Chair of the Melanoma and Skin Cancer (MASC) Trials Group (formerly the ANZMTG). He is a member of the BCNA Medical Advisory Committee. Andrew is Breast sub-editor for the ANZ Journal of Surgery, and an editorial board member of the Journal of Surgical Oncology. He is founding co-director of the University of Sydney’s Graduate Certificate in Breast Surgery and Unit Co-ordinator for the Malignant Breast Disease and Multidisciplinary Teams unit of study. Andrew is a Faculty Member and Research Committee member of Melanoma Institute Australia. Andrew’s current research interests investigate issues around quality assurance and safe de-escalation in surgery, safe introduction of new surgical techniques and promoting multidisciplinary clinical trial involvement by surgeons. He is involved in clinical and translational research on aspects of breast cancer and melanoma. He has been an author on about 200 peer reviewed publications and co-authored 4 book chapters. He teaches students at the University of Sydney’s, Northern Clinical School and a member of the MIA Translational Hub.


2021 and 2022

  • Alec A Winder BM FRACS1, Andrew J Spillane MD FRACS1,3, Samriti Sood MBBS FRACS1,2,3, Merran McKessar MBBS FRANZCR1, Deborah Cohn MBBS FRACP1, Kylie Snook BMed (Hons) FRACS1,5
  • Andrea L Smith; Caroline Watts; Michael Henderson; Georgina Long; Frances Rapport; Robyn Saw; Richard Scolyer; Andrew Spillane; John Thompson; Anne Cust Factors influencing acceptance, adoption and adherence to sentinel node biopsy recommendations in the Australian Melanoma Management Guidelines: a qualitative study using an implementation science framework Implementation Science Communications. Accepted 20092022
  • Anna K Lawless 1 2 3, David J Coker 1 2 3, Serigne N Lo 1 2, Tasnia Ahmed 1, Richard A Scolyer 1 2 4 5, Sydney Ch'ng 1 2 3 6, Omgo E Nieweg 1 2 3, Kerwin Shannon 1 3, Andrew Spillane 1 2 7, Jonathan R Stretch 1 2 3, John F Thompson 1 2 3, Robyn P M Saw. Clinicopathological Characteristics Predicting Further Recurrence and Survival Following Resection of In-Transit Melanoma Metastases. Ann Surg Oncol 2022 Jun 30. doi: 10.1245/s10434-022-11997-0.
  • Rebecca C. Simpson*, Erin R. Shanahan*, Marcel Batten*, Irene L.M. Reijers*, Mark Read#, Ines P. Silva#, Judith M. Versluis#, Rosilene Ribeiro, Alexandra S. Angelatos, Jian Tan, Chandra Adhikari, Alexander M. Menzies, Robyn P.M. Saw, Maria Gonzalez, Kerwin F. Shannon, Andrew J. Spillane, Rebecca Velickovic, Laurence Macia, Andrew J. Holmes, James S. Wilmott, Christian U. Blank, Richard A. Scolyer, Georgina V. Long (*#these authors have contributed equally). Diet-driven microbial ecology underpins associations between cancer immunotherapy outcomes and gut microbiome. 23.7.22: accepted for publication to Nature Medicine
  • LM Reijers1, AM Menzies3,4,5*, ACJ van Akkooi10,*, JM Versluis1*, NMJ vd Heuvel2*, RPM Saw3,4, TE Pennington3, E Kapiteijn6, AAM van der Veldt7, KPM Suijkerbuijk8, GAP Hospers9, EA Rozeman1, WMC Klop10, WJ v Houdt10, K Sikorska11, JA van der Hage12, DJ Grünhagen13, MW Wouters10,14, AJ Witkamp15, CL Zuur10, JM Lijnsvelt1, A Torres11, LG Grijpink-Ongering11, M Gonzalez3, K Jóźwiak16, C Bierman17, KF Shannon3, S Ch’ng3, AJ Colebatch18, AJ Spillane3,4, JABG Haanen1,19,20, RV Rawson18, BA van de Wiel19, , L vd Poll2,21,22, RA Scolyer3,4,18, AH Boekhout2#, GV Long3,4,5#, CU Blank1,19,20# Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial", Nature Medicine 2022 accepted for publication 29042022
  • Gabrielle Metz *, Kylie Snook, Samriti Sood, Sally Baron-Hay, Andrew Spillane, Gillian Lamoury, Susan Carroll. Breast radiotherapy after oncoplastic surgery; a multidisciplinary approach (Review) Cancers Accepted 22032022
  • Mary-Ann El Sharouni1,2, Richard A Scolyer1,3,4, Carla H van Gils5, Sydney Ch’ng1,3,6, Omgo Nieweg1,3,6, Thomas E Pennington1,6, Robyn PM Saw1,3,6, Kerwin Shannon1,6, Andrew Spillane1,3,6, Jonathan Stretch1,3,6, Arjen J Witkamp7, Vigfús Sigurdsson2, John F Thompson1,3,6*, Paul J van Diest8* & Serigne N Lo1,3 *Time interval between diagnostic excision-biopsy of a primary melanoma and sentinel node biopsy: effects on the sentinel node positivity rate and survival. Eur J Cancer 2022 accepted Jan
  • Mary-Ann El Sharouni1,2, Richard A Scolyer1,3,4, Carla H van Gils5, Sydney Ch’ng1,3,6, Omgo Nieweg1,3,6, Thomas E Pennington1,6, Robyn PM Saw1,3,6, Kerwin Shannon1,6, Andrew Spillane1,3,6a, Jonathan Stretch1,3,6, Arjen J Witkamp7, Vigfús Sigurdsson2, John F Thompson1,3,6*, Paul J van Diest8* & Serigne N Lo1,3*Effect of the time interval between melanoma diagnosis and sentinel node biopsy on the size of metastatic tumour deposits in node-positive patients. Eur J Cancer 2022 Accepted Jan.
  • Caroline G Watts1,2, Andrew J Spillane3,4,5,6, Michael A Henderson7,8, Australian Melanoma Centre of Research Excellence Study Group*, Anne E Cust1,3 * Australian Melanoma Centre of Research Excellence Study Group:
  • Alexander C.J. van Akkooi, MD, PhD1, 19, Tina J. Hieken, MD2, 19, Elizabeth M. Burton, MBA3, 19, Charlotte Ariyan4, 19, Salvatore Asero5, 19, Matthew S. Block, MD, PhD2, 19, Genevieve Boland6, 19, Corrado Caraco7, 19, Scott Davidson8, 19, Joao Duprat, Mark Faries9, 19, Jeffrey Gershenwald3, 19, Dirk Grunhagen, MD, PhD10, 19, David E. Gyorki11, 19, Dale Han12, 19, Andrew Hayes, MA PhD FRCS (gen)13, 19, Winan J van Houdt, MD, Phd1, 19, George Karakousis14, 19, Martin Klop, MD, PhD1, 19, Michael C. Lowe15, 19, Roger Olofsson, MD, PhD, Merrick I. Ross3, 19, Piotr Rutkowski, Robyn P.M. Saw16, 19, Vernon K. Sondak, MD 17, 19, Andrew J. Spillane, MD16, 19, Alessandro A.E. Testori, MD, PhD18, 19, John Thompson16, 19, Jonathan S. Zager, MD17, 19, Charlotte Zuur, MD, PhD1, 19, Jennifer A. Wargo, MD3,19. Neoadjuvant Systemic Therapy (NAST) in Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC). Ann Surg Oncol Accepted Dec 2021
  • F Newell, IP da Silva, PA Johansson, AM Menzies, JS Wilmott, V Addala, ... Multi-omic profiling of checkpoint inhibitor-treated melanoma: identifying predictors of response and resistance and markers of biological discordance CANCER-CELL-D-20-01268R3 Accepted December 2021
  • Andrew T Li, Kavita Vakharia, Serigne N Lo, Alexander HR Varey, Matteo S Carlino, Robyn PM Saw, Kerwin F Shannon, Julie R Howle, Thomas E Pennington, Jonathan R Stretch, Omgo E Nieweg, Andrew J Spillane, Georgina V Long, Alexander M Menzies, Richard A Scolyer, John F Thompson, Sydney Ch’ng.Survival outcomes of salvage metastasectomy after failure of modern-era systemic therapy for melanoma.Ann Surg Oncol 10/2021
  • ILM Reijers1, RV Rawson2,3,4,5, AJ Colebatch2,3,4,5, EA Rozeman1, AM Menzies2,3,6, ACJ van Akkooi7, KF Shannon2,3,4,5, MW Wouters7, RPM Saw2,3,4,5, WJ van Houdt7, CL Zuur8, J Hansson9, OE Nieweg2,3,4,5, S Ch’ng2,3,5, WMC Klop8, AJ Spillane2,3,6, GV Long2,3,6*, RA Scolyer2,3,4,5*, BA van de Wiel10* and CU Blank1,11,12* Neoadjuvant Checkpoint Inhibitor Therapy in Melanoma: Representativeness of the Index Lymph Node for Total Nodal Basin in Pathological Response Assessment. JAMA Accepted 11/ 2021
  • RV Rawson, C Adhikari, C Bierman, SN Lo, E Shklovskaya, EA Rozeman, ...Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma. Annals of Oncology 32 (6), 766-777
  • Kathy Dempsey, Erin Mathieu, Meagan Brennan, Kylie Snook, Julia Hoffman, Ian Campbell, Jenni Scarlet, Heather Flay, April Wong, Frances Boyle, Madeleine King, Andrew Spillane. The role of choice in patient-reported outcomes on body image at 4 years post-mastectomy for breast cancer: A longitudinal prospective cohort study. Psycho-oncology 2021 (Accepted 29 July 2021). DOI: 10.1002/pon.5776
  • Downs JS, Subramaniam S, Henderson MA, Paton E, Spillane AJ, Mathy JA, Gyorki DE. A Survey of Surgical Management of the Sentinel Node Positive Melanoma Patient in the post-MSLT2 Era. J Surg Oncol. 2021 Aug 18. doi: 10.1002/jso.26641. Accepted July.
  • Karina Aivazian, Tasnia Ahmed, Mary-Ann El Sharouni, Jonathan Stretch, Robyn Saw, Andrew Spillane, Kerwin Shannon, Sydney Ch'ng, Omgo Nieweg, John Thompson, Serigne Lo, and Richard Scolyer. Histological Regression in Melanoma: Impact on Sentinel Lymph Node Status and Survival." Modern Pathology [Paper #MP-21-0011-A-RR],2021 accepted May 12
  • Liyanage U, MacGregor S, Bishop DT, Shi J, An J, Ong JS, Han X, Scolyer RA, Martin NG, Medland SE, Byrne EM, Green AC, Saw RPM, Thompson JF, Stretch J, Spillane A, Jiang Y, Tian C; 23andMe Research Team, Gordon SG, Duffy DL, Olsen CM, Whiteman DC, Long GV, Iles MM, Landi MT, Law MH. Multi-trait genetic analysis identifies auto-immune loci associated with cutaneous melanoma. J Invest Dermatol. 2021 Nov 20:S0022-202X(21)02513-6. doi:10.1016/j.jid.2021.08.449. Online ahead of print
  • Sydney Ch’ng 1-4, Semra Uyulmaz 3,4, Matteo S. Carlino 1,2,5, Thomas E. Pennington1-3, Kerwin Shannon1-4, Michael Rtshiladze1,3, Jonathan Stretch1-3, Omgo E. Nieweg 1-3, Alexander Varey1,2,5, Ines Pires da Silva1, Serigne Lo1,2, Andrew J. Spillane1,2,6, Richard A Scolyer1-3, Georgina V. Long1,2,6, Angela Hong1,7, Robyn P. M. Saw 1-3, John F. Thompson1-3, Alexander M. Menzies1,2,6 Re-defining the Role of Surgery in the Management of Patients with Oligometastatic Stage IV Melanoma in the Era of Effective Systemic Therapies. European Journal of Cancer 2021 Accepted May 2021.
  • Flitcroft K, Brennan ME, Spillane AJ. Inaugural Roundtable on breast reconstruction practice in Australia. Background, process and recommendations.: Report on breast reconstruction roundtable Australasian Journal of Plastic Surgery."2021 accepted 15032021.
  • John F. Thompson, Robyn P.M. Saw, Jo Dalton, Jonathan R. Stretch, Andrew J. Spillane, Natalie Osborne, Gabrielle J. Williams and Serigne N. Lo. Treatment of in-transit melanoma metastases using intralesional PV-10. Melanoma Research 2021, 31:232–241.
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  • Abd El-Aziz YS, Spillane AJ, Jansson P, Sahni S.Role of ABCB1 in Mediating Chemo-resistance of Triple Negative Breast Cancers. Biosci Rep 2021 Feb 5;BSR20204092. doi: 10.1042/BSR20204092. Online ahead of print.


  • Smith AL, Watts CG, Robinson S, Schmid H, Goumas C, Mar VJ, Thompson J, Rapport F, Braithwaite J, Gyorki DE, Henderson M, Hong AM, Kelly JW, Long GV, Menzies, AM, Morton RL, Saw RPM, Scolyer RA, Spillane AJ, Mann GJ, Cust AE. Knowledge and attitudes of Australian dermatologists towards sentinel lymph node biopsy for melanoma: a mixed methods study. Australasian Journal of Dermatology, 2020 Accepted 19/10/2020
  • EA Rozeman,1 EP Hoefsmit,2* ILM Reijers,1* RPM Saw,3,4,5 JM Versluis1, O Krijgsman,2 P Dimitriadis,2 K Sikorska,6 BA van de Wiel,7 H Eriksson,8 M Gonzalez,9 A Torres Acosta,6 LG Grijpink-Ongering, 6 K Shannon,3,5 JBAG Haanen,1,2 J Stretch,3,4,5 S Ch’ng,3,4,5 OE Nieweg,3,4, 5 HA Mallo,1 S Adriaansz,1 R Kerkhoven,10 S Cornelissen,11 A Broeks,11 WMC Klop,12 CL Zuur,12 W van Houdt,12 DS Peeper,2 AJ Spillane,3,4 ACJ van Akkooi,12 RA Scolyer,13,14 TNM Schumacher,2 AM Menzies,9,15,16 GV Long9,15,16 and CU Blank1 Two and Four Year Relapse-free Survival Update and Baseline Biomarker Analyses from trials of Neoadjuvant and Adjuvant Ipilimumab plus Nivolumab in Stage III Melanoma. Nature Medicine 2020 accepted October.
  • Hubbley S, Barton R, Snook KL, Spillane AJ. Sentinel Node Occult Lesion Localisation (SNOLL) Technique for Impalpable Breast Cancer. ANZ Journal of Surgery 2020 Accepted 13102020.
  • Flitcroft K, Brennan ME, Spillane AJ. Optimal referral pathways for preference-sensitive treatment options: A case study of breast reconstruction in Australia. Archives of Breast Cancer Accepted 10/10/2020
  • Alexander M. Menzies, MD PhD*1,2, Rodabe N. Amaria*3, Elisa A. Rozeman*4, Alexander C. Huang*5,6, Michael T. Tetzlaff*3, Bart A. van de Wiel*4, Serigne Lo*1, Ahmad Tarhini8, Hussein A. Tawbi3, Elizabeth M. Burton3, Thomas Pennington1,7, Robyn PM Saw1,7, Xiaowei Xu5, Giorgos C. Karakousis5,6, Paolo A. Ascierto9, Andrew J. Spillane1,2, Alexander C.J. van Akkooi4, Tara C. Mitchell^5,6, Michael A. Davies^3, Richard A. Scolyer^1,7, Jennifer A. Wargo^3, Christian U. Blank^4, Georgina V. . Pathological response and survival with neoadjuvant therapy in melanoma: a pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC). Nature Medicine. Accepted September 2020
  • Whole genome sequencing of acral melanoma reveals genomic complexity and diversity. Nature Communications Accepted September 2020
  • Nickel B, McCaffery K, Houssami N, Jansen J, Saunders C, Spillane A, Rutherford C, Dixon A, Barratt A, Stuart K , Roberston G, Herch J. Views of healthcare professional about the role of Active Monitoring in the management of Ductal Carcinoma in Situ (DCIS): qualitative interview study. The Breast, accepted 8 September 2020
  • M. T. Tetzlaff1,2*y, C. Adhikari3 y, S. Lo3 y, R. V. Rawson3 ,4 ,5, R. N. Amaria6, A. M. Menzies3 ,7 , J. S. Wilmott3 , P. M. Ferguson3 ,4 ,5, M. I. Ross8 , A. J. Spillane3 ,7 , K. A. Vu1, J. Ma9, J. Ning9, L. Haydu8 , R. P. M. Saw3 ,4 , J. A. Wargo8 ,10 , H. A. Tawbi6 , J. E. Gershenwald8 ,11, G. V. Long3 ,7 z, M. A. Davies2,6 ,12z & R. A. Scolyer3 ,4 ,5. Histopathological features of complete pathological response predict recurrence-free survival following neoadjuvant targeted therapy for metastatic melanoma. Ann Oncol 2020:
  • Olofsson Bagge R, Kicinski M, Faries MB, Gyorki DE, Isaksson K, Katsarelias D, Lo S, Moncrieff M, Spillane A, Suciu S, van Akkooi A. Comment on "Factors Affecting Sentinel Node Metastasis in Thin (T1) Cutaneous Melanomas: Development and External Validation of a Predictive Nomogram". J Clin Oncol. 2020 Jul 23:JCO2001680. doi: 10.1200/JCO.20.01680. Online ahead of print. PMID: 32701414 
  • Law MH, Aoude LG, Duffy DL, Long GV, Johansson PA, Pritchard AL, Khosrotehrani K, Mann GJ, Montgomery GW, Iles MM, Cust AE, Palmer JM; Melanoma GWAS Consortium, Shannon KF, Spillane AJ, Stretch JR, Thompson JF, Saw RPM, Scolyer RA, Martin NG, Hayward NK, MacGregor S. Multiplex melanoma families are enriched for polygenic risk. Hum Mol Genet. 2020 Jul 27:ddaa156. doi: 10.1093/hmg/ddaa156. Online ahead of print. PMID: 32716505
  • Mohammed Kashani-Sabet, MD 1; James R. Miller, III, PhD1; Serigne Lo, PhD 2,3; Mehdi Nosrati, BS1; Jonathan R. Stretch, MBBS 2,3,4; Kerwin F. Shannon, MBBS 2,3,4; Andrew J. Spillane, MD 2; Robyn P. M. Saw, MS2,3,4; James E. Cleaver, PhD5; Kevin B. Kim, MD1; Stanley P. Leong, MD1; John F. Thompson, MD2,3,4;and Richard A. Scolyer, MD 2,3,4,6 . Reappraisal of the prognostic significance of mitotic rate supports its reincorporation into the melanoma staging system. Cancer 2020 accepted.
  • Lo et al. 2020 “Improved Risk Prediction Calculator for Sentinel Node Positivity in Patients With Melanoma: The Melanoma Institute Australia Nomogram.” Journal of Clinical Oncology In press: JCO1902362 PMID:32530761
  • Alexander C. J. van Akkooi, MD, PhD1, and Andrew J. Spillane. ASO Author Reflections: The Landmark Series: Neoadjuvant Systemic Therapy (NAST) for Stage 3 Melanoma Patients: A Potential Paradigm Shift in Management. Ann Surg Oncol (2020) 27:2201–2202.
  • Spillane AJ, A Menzies, van Akkooi A. ASO-2020-02-0230.R1 The Landmark Series: Neoadjuvant Systemic Therapy (NAST) for Stage 3 Melanoma Patients – a potential paradigm shift in management. Ann Surg Oncol 2020 May 7. doi: 10.1245/s10434-020-08570-y. [Epub ahead of print]
  • Christopher G Harris 1,2, Serigne Lo 1,3, Tasnia Ahmed 1, Richard A Scolyer 1,2,3, Peter M Ferguson 1,2,3, Rooshdiya Karim 2, T Quoc Lam 2, Kenneth K Lee 1,2, Kerwin F Shannon 1,2,3, Andrew J Spillane 1, 3, 4, Jonathan R Stretch 1,2,3, John F Thompson 1,2,3 and Robyn PM Saw 1,2,3 Primary dermal melanoma: clinical behaviour, prognosis and treatment. EJSO 2020. Available online 1 May 2020.
  • Haydu LE1, Lo SN2,3, McQuade JL4, Amaria RN4, Wargo J1, Ross MI1, Cormier JN1, Lucci A1, Lee JE1, Ferguson SD5, Saw RPM2,3,6, Spillane AJ2,3,7, Shannon KF2,7, Stretch JR2,3,7, Hwu P8, Patel SP4, Diab A4, Wong MKK4, Glitza Oliva IC4, Tawbi H4, Carlino MS2,3,9, Menzies AM2,3,7, Long GV2,3,7, Lazar AJ10,11,12,13, Tetzlaff MT10,13, Scolyer RA2,3,6, Gershenwald JE1, Thompson JF2,3,7, Davies MA4. Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma. J Clin Oncol. 2020 May 1;38(13):1429-1441. doi: 10.1200/JCO.19.01508. Epub 2020 Jan 28
  • Frances Rapport,*1 Andrea L Smith,*1 Anne E Cust,2,3 Graham Mann,3,4 Caroline Watts,2,5 David Gyorki,6 Michael Henderson,6 Angela Hong,3,7 John Kelly,8 Georgina Long,3,7 Victoria Mar,8 Rachael Morton,3,9 Robyn Saw,3,7 Richard Scolyer,3,7 Andrew Spillane,3,7 John Thompson,3 Jeffrey Braithwaite1 Identifying challenges to implementation of clinical practice guidelines for sentinel lymph node biopsy in patients with melanoma in Australia: protocol paper for a mixed methods study. BMJ Open 2020 Feb 27;10(2):e032636. doi: 10.1136/bmjopen-2019-032636.
  • Watts CG, Smith AL, Robinson S, Chang C, Schmid H, Goumas C, Kelly J,, Hong A, Scolyer R, Long G, Spillane A, Henderson M, Gyorki D, Mar V, Morton RM, R Saw, Varey A, Mann GJ, Thompson J , Cust AE. Australian general practitioners’ attitudes and knowledge of sentinel lymph node biopsy in melanoma management. Accepted The Australian Journal of General Practice, January 24, 2020
  • Salindera S, M, Spillane AJ. What are the appropriate thresholds for High Quality Performance Indicators for Breast Surgery in Australia and New Zealand? THEBREAST; 2020;51: 94-101.
  • Flitcroft K, Brennan ME, Salindera S, Spillane AJ. Increasing access to breast reconstruction for women living in underserved non-metropolitan areas of Australia. Supportive Care in Cancer. 2020 Jun;28(6):2843-2856. doi: 10.1007/s00520-019-05130-3. Epub 2019 Nov 15
  • Flitcroft K, Brennan ME, Spillane AJ. ANS-2019-00748.R1. On the frontiers of change”: Breast surgeons’ views on demarcation between surgical sub-specialties in Australia. Type: Original Article ANZ J Surg 2020;90(3) 317 324.
  • Julia Chen MBBS, BSc(Med)Hons1,*, Neshanth Easwaralingam MBBS, FRACS1,*, Sanjay Warrier MBBS, FRACS2, Andrew Ong MBChB, FRACS3, Emma-Kate Carson MBChB, FRACP1,3, Cindy Mak MBBS, FRACS2, Kylie Snook MBBS, FRACS4 , Kate Middleton, MBBS, FRCPA1, Andrew Parker MBBS, FRCPA1, Carlo Palmieri MRCP, PhD5, Andrew Spillane MD, FRACS4, G Bruce Mann FRACS, PhD6, Elgene Lim FRACP, PhD1,*, Davendra Segara FRACS, PhD1 Window of Opportunity Treatment in Breast Cancer: Review Article ANZ J Surg 2020 Jan;90(1-2):34-40. doi: 10.1111/ans.15487. Epub 2019 Nov 26
  • Nijhuis A, Thompson JF, Spillane AJ, Saw RPM, Menzies A, Uren R, Nieweg O. Current management of patients with melanoma who are found to be sentinel node-positive. ANZ J Surg 2020 Volume90, Issue4;491-496;


  • Russell Diefenbach, Jenny Lee, Dario Strbenac, Jean Yang, Alexander Menzies, Matteo Carlino, Georgina Long, Andrew Spillane, Jonathan Stretch, Robyn Saw, John Thompson, Sydney Ch'ng, Richard Scolyer, Richard Kefford, Helen Rizos. Genomic landscape of patient-matched tumor and circulating cell-free DNA in metastatic melanoma Cancers. 2019;11, 1905 DOI: 10.3390/cancers11121905
  • Michael A Henderson, John Spillane, Michael Hughes, Andrew Spillane, B Mark Smithers, John F Thompson. New treatment paradigms for clinically-apparent metastatic melanoma in regional lymph nodes. ANZ J Surg 2019 Oct;89(10):1187-1189. doi: 10.1111/ans.15407
  • Yingyu Feng, Kathy Flitcroft, Marina T. van Leeuwen, Adam G Elshaug, Andrew Spillane, Sallie-Anne Pearson. Patterns of immediate breast reconstruction in NSW Australia: a population-based study. ANZJ Surg 2019 Oct;89(10):1230-1235. doi: 10.1111/ans.15381. Epub 2019 Aug 16
  • Georgina V Long, Robyn P M Saw, Serigne Lo, Omgo E Nieweg, Kerwin F Shannon, Maria Gonzalez, Alexander Guminski, Jenny H Lee, Hansol Lee, Peter M Ferguson, Robert V Rawson, James S Wilmott, John F Thompson, Richard F Kefford, Sydney Ch’ng, Jonathan R Stretch, Louise Emmett, Rony Kapoor, Helen Rizos, Andrew J Spillane, Richard A Scolyer, Alexander M Menzies. Neoadjuvant dabrafenib combined with trametinib for resectable, stage IIIB–C, BRAFV600 mutation-positive melanoma (NeoCombi): a single-arm, open-label, single-centre, phase 2 trial. Lancet Oncol 2019 Jul;20(7):961-971. doi: 10.1016/S1470-2045(19)30331-6. Epub 2019 Jun 3
  • Felicity Newell, Yan Kong, James Wilmott, Peter Johansson, Peter Ferguson, Chuan Liang Cui, Zhongwu Li, Stephen Kazakoff, Hazel Burke, Tristan Dodds, Ann-Marie Patch, katia Nones, Varsha Tembe, Ping Shang, Louise van der Weyden, Kim Wong, Oliver Holmes, Serigne Lo, Conrad Leonard, Scott Wood, Qinying Xu, Robert Rawson, Pamela Mukhopadhyay, Reinhard Dummer, Mitchell Levesque, Göran Jönsson, Xuan Wang, Iwei Yeh, Hong Wu, Nancy Joseph, Boris Bastian, Georgina Long, Andrew Spillane, Kerwin Shannon, John Thompson, Robyn Saw, David Adams, Lu Si, John Pearson, Nicholas Hayward, Nicola Waddell, Graham Mann, Jun Guo, and Richard Scolyer. Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets. Nature Communications 2019 Jul 18;10(1):3163. doi: 10.1038/s41467-019-11107-x
  • Spillane AJ, Flitcroft K, Warrier S, Katelaris A. Evaluation of a structured clinical program and formal coursework in breast surgeon training in Australia and New Zealand. EJSO 2019 Oct;45(10):1821-1826. doi: 10.1016/j.ejso.2019.05.014. Epub 2019 May 16.
  • Amaria, Rodabe N ; Menzies, Alexander M ; Burton, Elizabeth M ; Scolyer, Richard A ; Tetzlaff, Michael T ; Antdbacka, Robert ; Ariyan, Charlotte ; Bassett, Roland ; Carter, Brett ; Daud, Adil ; Faries, Mark ; Fecher, Leslie A ; Flaherty, Keith T ; Gershenwald, Jeffrey E ; Hamid, Omid ; Hong, Angela ; Kirkwood, John M ; Lo, Serigne ; Margolin, Kim ; Messina, Jane ; Postow, Michael A ; Rizos, Helen ; Ross, Merrick I ; Rozeman, Elisa A ; Saw, Robyn P M ; Sondak, Vernon ; Sullivan, Ryan J ; Taube, Janis M ; Thompson, John F ; van de Wiel, Bart A ; Eggermont, Alexander M ; Davies, Michael A ; Andrews, Miles C ; Berry, Donald A ; Block, Matthew S ; Boland, Genevieve M ; Bollin, Kathryn B ; Carlino, Matteo S ; Carvajal, Richard D ; Cohen, Jonathan ; Davar, Diwakar ; Delman, Keith A ; Dummer, Reinhard ; Farwell, Michael D ; Fisher, David E ; Fusi, Alberto ; Glitza, Isabella C ; de Gruijl, Tanja D ; Gyorki, David E ; Hauschild, Axel ; Hieken, Tina J ; Larkin, James ; Lawson, David H ; Lebbe, Celeste ; Lee, Jeffrey E ; Lowe, Michael C ; Luke, Jason J ; Mcarthur, Grant A ; Mcdermott, David F ; Mcquade, Jennifer L ; Mitchell, Tara C ; Petrella, Teresa M ; Prieto, Peter A ; Puzanov, Igor ; Robert, Caroline ; Salama, April K ; Sandhu, Shaneen ; Schadendorf, Dirk ; Shoushtari, Alexander N ; Sosman, Jeffrey A ; Swetter, Susan M ; Tanabe, Ken K ; Turajlic, Samra ; Tyler, Douglas S ; Woodman, Scott E ; Wright, Frances C ; Zager, Jonathan S ; Ascierto, Paolo A ; Spillane, Andrew J ; van Akkooi, Alexander C J ; Wargo, Jennifer A ; Blank, Christian U ; Tawbi, Hussein A ; Long, Georgina V. Neoadjuvant Systemic Therapy in Melanoma:  Recommendations of the International Neoadjuvant Melanoma Consortium. Lancet Oncol 2019 Jul;20(7):e378-e389. doi: 10.1016/S1470-2045(19)30332-8
  • Nicholas Zdenkowski1,2,3, Phyllis Butow4, Andrew Spillane1,5, Charles Douglas3, Kylie Snook5, Mark Jones6, Christopher Oldmeadow6, Sheryl Fewster7, Corinna Beckmore8, Frances M Boyle1,9 Patient-reported outcomes with neoadjuvant vs adjuvant systemic therapy for operable breast cancer.  Breast 2019 Aug;46:25-31. doi: 10.1016/j.breast.2019.04.003. Epub 2019 Apr 20
  • Elisa A Rozeman, MD; Alexander M Menzies, MD; Alexander C J van Akkooi, MD; Chandra Adhikari, MD; Bart van de Wiel, MD; Richard A Scolyer, MD; Oscar Krijgsman, PhD; Karolina Sikorska, PhD; Hanna Eriksson, MD; Annegien Broeks, PhD; Johannes V van Thienen, MD; Alexander Guminski, MD; Alex Torres, PhD; Sylvia ter Meulen, CNS; Anne Miek Koenen, CNS; Kerwin Shannon, MD; Loes M. Pronk, PhD; Maria Gonzalez, Sydney Ch’ng, MD; Hanna Emanuelsson, MD; Lindsay G Grijpink-Ongering, BSc; Jonathan Stretch, MD ; Stijn Heijmink, MD; Harm van Tinteren, PhD; John B A G Haanen, MD; Omgo Nieweg, MD; Willem M C Klop, MD; Lotje Zuur, MD; Robyn P M Saw, MD; Winan J van Houdt, MD; Andrew J Spillane, MD; Johan Hansson, MD; Ton N. Schumacher, PhD; Georgina V. Long, MD; and Christian U Blank, MD. Identification of the optimal combination scheme of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma: a multicentre randomized phase 2 study (OpACIN-neo). Lancet Oncology 2019
  • Jenny H Lee1,2, Robyn PM Saw2,3,4, John F Thompson2,3,4, Serigne Lo2,4, Andrew J Spillane2,5, Kerwin F Shannon2,6, Jonathan Stretch2, Julie Howle7, Alexander M Menzies2,4,5, Matteo S Carlino2,4,7, Richard F Kefford1,2,7, Georgina V Long2,4,5, Richard A Scolyer2,4,8, Helen Rizos1,2Pre-operative ctDNA predicts survival in high risk stage III cutaneous melanoma patients. Ann Oncol 2019 May 1;30(5):815-822. doi: 10.1093/annonc/mdz075
  • Oh DD, Flitcroft K, Brennan ME, Snook KL, Spillane AJ. Outcomes of breast reconstruction in older women: Patterns of uptake and clinical outcomes in a large metropolitan practice. ANZ J Surg  2019 Jun;89(6):706-711. doi: 10.1111/ans.15145. Epub 2019 Apr 29
  • Gelareh Farshid, Michael Bilous, Adrienne Morey, Stephen Fox, Sunil Lakhani, Sherene Loi, Richard Bell, Andrew Spillane. ASCO CAP 2018 HER2 Testing Guidelines: Summary of Pertinent Recommendations for Practice in Australia. Pathology 2019 Jun;51(4):345-348. doi: 10.1016/j.pathol.2019.02.004. Epub 2019 May 7.
  • Spillane AJ, Hong A, Fogarty G. Re-examining the role of adjuvant radiation therapy. Journal of Surgical Oncology 2019 Jan;119(2):242-248. doi: 10.1002/jso.25329. Epub 2018 Dec 16
  • Brennan, Meagan E and Spillane, Andrew J. Breast symptoms in adolescents and young adults presenting to a specialist breast clinic [online].  Australian Journal of General Practice, Vol. 48, No. 3, Mar 2019: 146-151. Availability: ISSN: 2208-7958. [cited 19 May 20].


  • Oh DD, Flitcroft K, Brennan ME, Snook KL, Spillane AJ. Patient-reported outcomes of breast reconstruction in older women: Audit of a large metropolitan public/private practice in Sydney, Australia. Psycho-Oncology 2018 Dec;27(12):2815-2822. doi: 10.1002/pon.4895. Epub 2018 Oct 10
  • Erica B. Friedman, Tristan J. Dodds, Serigne Lo, Peter M.Ferguson, Matthew Beck, Robyn P.M. Saw, Jonathan R. Stretch, Kenneth J. Lee, Omgo E. Nieweg, Andrew J. Spillane, Richard A. Scolyer, John F.Thompson. Correlation Between Surgical and Histologic Margins in Melanoma Wide Excision Specimens. Ann Surg Oncol 2019 Jan;26(1):25-32. doi: 10.1245/s10434-018-6858-y. Epub 2018 Oct 16
  • James S. Wilmott1,9,11*§, Peter A. Johansson2*, Felicity Newell2*, Nicola Waddell2,3, Peter Ferguson1,4,9,11, Camelia Quek1,9,11, Katia Nones2, Ann-Marie Patch2, Ping Shang1,9,11, Antonia L. Pritchard2,5, Stephen Kazakoff 2,3, Oliver Holmes2,3, Conrad Leonard2,3, Scott Wood2,3, Robyn P. M. Saw1,4, Andrew J. Spillane1,9, Jonathan R. Stretch1,9, Kerwin F. Shannon1,4, 9, 11 , Richard F. Kefford1,6, Georgina V. Long1,9,11, John F. Thompson1,4,9,11, John V. Pearson2,3#, Graham J. Mann1,8#, Nicholas K. Hayward1,2#, Richard A. Scolyer1,4,9,11#.Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility. Int J Cancer 2019 Mar 1;144(5):1049-1060. doi: 10.1002/ijc.31791. Epub 2018 Nov 21.
  • M. T. Tetzlaff1,2,*, J. L. Messina3, J. E. Stein4, X. Xu5, R. N. Amaria6, C. Blank7, B. Van De Wiel7, P. M. Ferguson8, R. V. Rwson8, M. I. Ross9, A. J. Spillane10, J. E. Gershenwald9,11, R.P.M. Saw8, T. Mitchell12, A. M. Menzies10, G. V. Long10, J. A. Wargo9,13, M. A. Davies2,6,14, V. G. Prieto1,15, J. M. Taube4,& and R. A. Scolyer8,& Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma. Ann Oncol 2018 Accepted June 14 2018 Aug 1;29(8):1861-1868. doi: 10.1093/annonc/mdy226
  • Azimi F1, Flitcroft K, Mathieu E, Karantonis R, Snook K, Spillane AJ. Low level laser treatment is ineffective for capsular contracture - results of the LaTCon randomized controlled trial. Plastic and Reconstructive Surgery PRS-D-17-02092R2 2018. Accepted 3/05/2018
  • Marc Moncrieff1*, David Gyorki2*, Robyn Saw3, Andrew Spillane3, Howard Peach4, Deemesh Oudit5, Jenny Geh6, Peter Dziewulski7, Ewan Wilson8, Paolo Matteucci9, Rowan Prtichard-Jones10, Roger Olofsson Bagge11, Frances Wright12, Nic Crampton13, Oliver Cassell14, Navid Jallali15, Adam Berger16, John Kelly17, Stephen Hamilton18, Amer Durrani19, Serigne Lo20, Elizabeth Paton20, Michael Henderson2. 1cm versus 2cm excision margins for pT2-pT4 primary cutaneous melanoma (MelMarT): A feasibility study. Ann Surg Oncol 2018 Accepted March
  • Breast Surgeons of Australia and NewZealand
  • The University of Sydney
  • Royal North Shore Hospital
  •  Australian Society Of Breast Disease
  • Mater Hospital A facility of ST Vincent's Health Australia
  • Fellow of the Royal Australasian College of Surgeons
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